A new debugger feature in Visual Studio 2010 that I really love is pinning debugger views (basically a watch in a floating window) of variables:
So when you break into the code again, you won't have to hover back over the interesting variable, you just need to look at the pinned item.
You can even set a comment on the pinned watch:
This allows you to pin multiple variables as well, from basically anything you could normally see in in debug view (as far as I can tell):
4bfd6dc3-3384-4227-a255-877a094f9ee8|0|.0